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SeSAMe Methylation Beta Estimation

Description

SeSAMe Methylation Beta Estimation is a workflow used in GDC methylation array harmonization.

Overview

SeSAMe Methylation Beta Estimation is used for methylation array harmonization at the GDC. Methylation array harmonization is performed with SeSAMe using raw tumor or normal methylation array files and generates beta values and masked intensities data, which removes potential genotype information.

Input

  • Raw Methylation Array

Output

  • IDAT (Data Type: Masked Intensities)
  • TXT (Data Type: Methylation Beta Value)

References

  1. Methylation Analysis
  2. SeSAMe Methylation Beta Values File Format

Categories: Workflow Type